Assignment Question
A literature review is a paper where the author presents the known data and background a research question builds from. This paper should have a well-stated introduction. Present PICO question. Citations here may be more foundational to present the content of the topic. Then, the collected literature should be presented in a way that gives an overview of each article (1-2 paragraphs for each article). Clearly present study particulars (participants, design, location, method, conclusion). The articles should be presented in a logical format that fits the question; this may be chronological, thematic, or methodological. The next section should include data analysis: themes, findings, and conclusions, then data strengths or shortcomings, and finally, identify deficits or gaps in data. Collectively restate from the article presentations. Comprehensive analysis. Do not forget a conclusion; restate for emphasis and clearly tie in the background to the presented data and future potential of a PICO question. APA 7th edition.
PICOT Question: Use of negative pressure wound therapy on a diabetic patient with stage 3 pressure ulcers compared with standard moist wound therapy.
P) Patient population/disease: In the modified intention-to-treat (ITT) population, 368 patients were randomized, and 345 participants were enrolled. Adult patients having a diabetic foot ulcer for at least four weeks and no contraindications to NPWT were eligible to participate. Healthcare setting: This German national investigation was conducted in 40 surgical and internal medicine inpatient and outpatient diabetes foot care facilities. Patient problem: The DiaFu study sought to assess the efficacy and safety of negative pressure wound therapy (NPWT) in patients with diabetic foot wounds in clinical practice. Consider the following: Patients were randomized in a 1:1 ratio stratified by study site and ulcer severity grade using a web-based tool in this controlled clinical superiority trial with blinded outcome assessment.
I)Intervention or issue of interest: Nursing interventions: According to local norms and guidelines, NPWT was compared to standard moist wound care (SMWC). General information: The wound closure rate (difference: n=4 (2.5% (95% CI-4.7% – 9.7%); p=0.53)) and time to wound closure (p=0.244) were not substantially different across the treatment arms in the ITT population. There were 191 subjects (NPWT 127; SMWC 64) who had missing endpoint evidence, early therapy termination, or unapproved treatment adjustments. There were 96 AEs in the NPWT arm and 72 AEs in the SMWC arm (p=0.007), although only 16 AEs were attributable to NPWT.
C) Comparison intervention or issue of interest: Comparing: Use of negative pressure wound therapy on a diabetic patient with stage 3 pressure ulcers compared with standard moist wound therapy.
O) Outcome of interest: Risk factors: The risk factors in general of unhealed wounds. Prevention of wounds: Daily foot care and monitoring, healthy diet, exercise, and annual doctor visits.
T) Time involved to demonstrate an outcome: The primary result was wound closure in 16 weeks. Amputations, time until appropriate wound bed preparation, wound size and wound tissue composition, pain and quality of life (QoL) within 16 weeks, and recurrences and wound closure within 6 months were the secondary outcomes. Alternative therapies to discuss: Abstinence, condoms, The mini-pill (Progesterone only pill).
Rubric Title page, numbers, in-text citations, reference page. PICO question stated. The background of the problem with reference to pathophysiology or social construct provided. Data included for all research articles: participant specifics, sample size, study design, measurement/data collection, and results/conclusions outlined. Articles are presented logically (chronological, thematic, or methodological). Presentation of analysis: themes, conclusions, data details, and gaps identified. PICO restated. Problem is clearly tied to the data presented, and the importance of further research from a NURSING viewpoint highlighted.
