Author: chris

Question 1: During translation, the identity of an amino acid attached to an incoming tRNA and added to the growing polypeptide is never checked. A proofreading step that hydrolyzed the previously formed peptide bond after an incorrect amino acid had been inserted into a growing polypeptide (analogous to the proofreading step of DNA polymerases) would be impractical. Why? 10 sentences max.
Question 2: A new polypeptide of 320 amino acids has been found. Analysis of the protein shows that it has high homology to the hexokinase family of enzyme. Thus, this protein was renamed Hexokinase V. It has a much lower Km than any hexokinase and a much higher Vmax than any Hexokinase.

⦁ Estimate the approximate molecular weight (in daltons) of this protein. (hint: you may have to do some research)

⦁ Why might it be good or bad if this new Hexokinase was present in the liver? 10 sentences max.

Question 4: Glycerol 3-phosphate is required for the biosynthesis of triacylglycerols. Adipocytes, specialized for the synthesis and degradation of triacylglycerols, cannot use glycerol directly because they lack glycerol kinase, which catalyzes the reaction:

How does adipose tissue obtain the glycerol 3-phosphate necessary for triacylglycerol synthesis?
Question 5: The glutamine synthetase of E. coli is independently modulated by various products of glutamine metabolism (see Fig. 22–8). In this concerted inhibition, the extent of enzyme inhibition is greater than the sum of the separate inhibitions caused by each product. For E. coli grown in a medium rich in histidine, what would be the advantage of concerted inhibition?

In an organization, there are many employment policies in the company handbook. This handbook is given to employeesat the start of the employer, employee relationship, and although generally not construed as a binding contract against the company in a later lawsuit over the policies, it governs the expectations of employees at the workplace. This Mini Project will have you analyze a company handbook as it relates to the company’s disability policy(ies) and provide a written reportof your findings. The report should be at least two pages in length. Please

Suppose the stock price is $25, there are 1.5 million shares of stock, the firm has $13.5 million of preferred stock, and $62 million of debt. Estimate
The total value
The WACC weights.
Write the WACC formula with the corresponding weights.
Estimate the cost of debt. Assume that you are issuing a 10 yr, 6% semiannual bond that sells for $1,015.72. (Use the excel formula)
Illustrate the before-tax cost of debt by showing the corresponding time line.
If the tax rate is 40%, what is the after-tax cost of debt?
What role do flotation costs play in the cost of debt? Explain.
Estimate the annual and quarterly cost of issuing preferred stock (use the cost of preferred stock formula studied in class). Assume the price of preferred stock is $104.35, 4% dividend,
$100 par (face) value and flotation costs (F) of 5%.
Draw the time line of preferred stock. Remember that dividends are paid quarterly.
Make sure your result is correct by estimating the cost of issuing preferred stock using the corresponding excel formula.
Use the CAPM Cost of Equity model to determine the cost of issuing common stock. Assume that the risk free rate is 3.2%, the market risk premium is 4% and the estimate of beta is 0.98.
Re write the WACC formula, substituting the values you have found in all the previous questions.
What is the hurdle rate? What does it mean? Explain.
Define an agency relationship.
If you are the only employee, and only your money is invested in the business, would any agency problems exist? Explain.
Would hiring additional people create agency problems? Explain.
Define the concept of Corporate Governance.
Suppose the government is running a budget deficit (previously the budget was balanced). Explain in detail what happens in the following markets:
Loanable Funds Market (draw a diagram)
Net Capital Outflow (draw a diagram)
Foreign-Currency Exchange (draw a diagram)
US Net exports
The January 29, 2014 nominal exchange rate for the following currencies were as follows:

Indirect Quotation January 29, 2014
Canadian Dollar 1.12
Euro 0.73
Japanese yen 102.34
Mexican Peso 13.41

Find the indirect quotation for December 4, 2015 and determine whether the currencies have appreciated or depreciated, and by how much.

For each currency, explain what is happening in the Foreign-Currency exchange market and in the trade balance between the US and each of these countries.

A Big Mac costs $3.50 in U.S., 60 pesos in Mexico. The nominal exchange rate is e = 17.05 pesos per $USD. Compute the real exchange rate.

Does the real exchange rate follows the “law of one price”? (i.e. follows the Purchasing Power Parity condition?). If it does not, what would be exchange rate according to the PPP condition? Explain.
If the CPI inflation rate is 12% in Mexico and 2% in the US, what will happen to the exchange rate? Explain.

Assignment 5: Capstone
Due Week 10 and worth 400 points

Select a publicly traded corporation for which you would like to work or are currently working.

Research the corporation on its own Website, the public filings on the Securities and Exchange Commission EDGAR database (http://www.sec.gov/edgar.shtml), in the University’s online databases, and any other sources you can find. The annual report will often provide insights that can help address some of these questions.

Write an eight to ten (8-10) page paper in which you:
1. Determine the impact of the company’s mission, vision, and primary stakeholders on its overall success.
2. Analyze the five (5) forces of competition to determine how they impact the company.
3. Create a SWOT analysis for the company to determine its major strengths, weaknesses, opportunities, and threats.
4. Based on the SWOT analysis, outline a strategy for the company to capitalize on its strengths and opportunities, and minimize its weaknesses and threats.
5. Discuss the various levels and types of strategies the firm may use to maximize its competitiveness and profitability.
6. Outline a communications plan the company could use to make the strategies you recommend above known to all stakeholders.
7. Select two (2) corporate governance mechanisms used by this corporation and evaluate how effective they are at controlling managerial actions.
8. Evaluate the effectiveness of leadership within this corporation and make at least one (1) recommendation for improvement.
9. Assess efforts by this corporation to be a responsible (ethical) corporate citizen and determine the impact these efforts (or lack thereof) have on the company’s bottom line. Provide specific examples to support your response.
10. Use at least five (5) quality references. Note: Wikipedia and other Websites do not quality as academic resources.

Your assignment must follow these formatting requirements:
• Be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides; references must follow APA or school-specific format. Check with your professor for any additional instructions.
• Include a cover page containing the title of the assignment, the student’s name, the professor’s name, the course title, and the date. The cover page and the reference page are not included in the required page length.

The specific course learning outcomes associated with this assignment are:
• Determine ways in which the vision, mission, and stakeholders of a firm impact that firm’s overall success.
• Identify how the six segments of the general environment affect an industry and its firms.
• Identify the five forces of competition.
• Analyze the external environment for opportunities and threats that impact the firm

While working an undercover detail in a neighborhood known for drug activity, you notice a vehicle stopped at the intersection waiting for the light to change. The man in the vehicle makes eye contact with you. You approach his vehicle and begin carrying on a conversation with him. You ask him if he needs anything, and he responds by asking you, “What do you have?” You ask him what he is looking for, and he tells you he is looking to score. You show him a small bag containing a white powdery substance; he asks how much, and you respond, “20 dollars.” He hands you a $20 bill, and you give him the bag and tip your hat to signal that the transaction was completed. At this time, the man drives off and is stopped a block away by a marked unit. The individual is placed under arrest for drug possession and purchasing drugs, and he is taken to jail.

The individual is charged with possession of a controlled substance. At his trial, he claimed that he was a victim of entrapment by the police. He was found guilty and sentenced to serve 5 years in jail and given credit for the 3 months he already had served in jail.

Primary Task Response: Your first task is to post your own Key Assignment Outline to the discussion area so that other students are able to review your plan. Attach your document to the main discussion post, and include any notes you feel are appropriate. The purpose of this assignment is to help improve the quality of the Key Assignment Draft you will complete next week.

Suppose the image below is your company’s network diagram after a merger and you have recently added access controls to your network. The CSO would like to:

• Change the internal network address to incorporate variable length subnet mask (VLSM) with EIGRP routing protocol.
• Set up all of the accountants on a separate VLAN.
• Create a VPN connection to allow accountants to access the accounting database from their home.

Write a two to three (2-3) page paper in which you:

1. Re-create the diagram provided in the assignment summary using VLSM, through the use of graphical tools in Microsoft Visio or an open source alternative such as Dia. (The starting address is 172.16.0.0.) Note: The graphically depicted solution is not included in the required page length.
2. Specify the commands that you would use to set up the routers to use EIGRP.
3. Outline the requirements to set up a VLAN and VPN access for the accountants.
4. Specify the VLAN assignment, and incorporate a Spanning Tree protocol into your design to eliminate loops.

Your assignment must follow these formatting requirements:

• Be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides; citations and references must follow APA or school-specific format. Check with your professor for any additional instructions.
• Include a cover page containing the title of the assignment, the student’s name, the professor’s name, the course title, and the date. The cover page and the reference page are not included in the required assignment page length.
• Include charts or diagrams created in Visio or an equivalent such as Dia. The completed diagrams / charts must be imported into the Word document before the paper is submitted.

The specific course learning outcomes associated with this assignment are:

• Describe and implement Virtual Local Area Networks (VLANs) on a computing network.
• Compare and contrast dynamic routing, distance vector routing, and link-state routing protocols.
• Use technology and information resources to research issues in Internetworking.
• Write clearly and concisely about basic internetworking using proper writing mechanics a

Assignment 5: Change Management Plan

Due Week 10 and worth 300 points

In this assignment, you will combine the previous four (4) assignments into a proposal that you could present to the executive leadership and board members. You will argue the value of the change management plan to the overall success of the organization. Add to your previous submissions a plan for sustaining the change in the long run.

Write a six to ten (6-10) page paper in which you:

Section I: Organization: Describe the organization and comment on the HR change that the organization should make. Utilize effective diagnostic tools to assess the organizations ability to change. Support assertions with theoretical evidence.

1. Describe the company in terms of industry, size, number of employees, and history.
2. Analyze in detail the current HR practice, policy, process, or procedure that you believe should be changed.
3. Formulate three (3) valid reasons for the proposed change based on current change management theories.
4. Appraise the diagnostic tools that you can use to determine an organization’s readiness for change. Propose two (2) diagnostic tools which you can utilize to determine if the organization is ready for change. Defend why you believe the diagnostic tools selected are the best choice for diagnosing change in the organization.
5. Using one (1) of the diagnostic tools you selected, assess the organization’s readiness for change.
   1. Provide results of the diagnostic analysis
   2. Explain the results
6. Interpret whether or not the organization is ready for change. Substantiate your conclusion by referencing current change management theories.

Section II: Kotter Change Plan: Utilizing the Kotter eight (8) step method of change, create a solid change management plan for the HR initiative you identified as requiring improvement.

1. Ascertain how each of the steps applies to your specific organization.
2. Develop a strategy that illustrates how you would address each of the eight (8) stages of change:
   1. Establishing a sense of urgency
   2. Creating coalition
   3. Developing vision and strategy
   4. Communicating the vision
   5. Empowering broad-based action
   6. Generating short-term wins
   7. Consolidating gains and producing more change
   8. Anchoring new approaches into the culture

Section III: Resistance and Communication: Research methods of minimizing resistance to change and create plan to address resistance within your change management initiative.

1. Diagnose the reasons for resistance to change.
2. Interpret the potential causes of resistance in the organization. Identify and describe three (3) potential causes of resistance to your change plan. Identify and describe three (3) potential sources of resistance to your change plan.
3. Create a plan for minimizing possible resistance to your change management plan.
4. Elaborate on the relationship between resistance to change and communication.
5. Evaluate three (3) communication strategies.
6. Recommend one (1) communication strategy that would be applicable to your organization. Diagnose why this communication strategy is best for your organization.
7. Create a solid communication plan for your change initiative.

Section IV: Sustaining Change: Research methods of sustaining change in organizations and create a plan for sustaining proposed change.

1. Recommend two (2) strategies for sustaining change:
   1. Diagnose the two (2) theories from a scholarly perspective
   2. Evaluate why the strategies selected are viable for the organization

Section V: Presentation: Create a visually appealing and informative presentation espousing the importance of the change management plan you developed.

1. Create a ten to fifteen (10-15) slide PowerPoint presentation to submit to executive leadership and board members outlining and describing your recommended change. Include the following criteria:
   1. Be creative in your design so that is appealing to others.
   2. Ensure that all of the MAJOR points of the plan are covered.
   3. Create bulleted speaking notes for your presentation to the shareholders in the Notes section of the PowerPoint. Note: You may create or assume any fictitious names, data, or scenarios that have not been established in this assignment for a realistic flow of communication.
   4. Use a professional technically written style to graphically convey the information.
   5. Create a video of yourself presenting the presentation to key stakeholders. Note: View the “Creating a Presentation for Your Course” playlist, located here for tutorials on creating and submitting video assignments.

Section VI: References: Utilize good scholarly research skills and writing skills to develop a solid change plan and presentation.

1. Use at least ten (10) quality academic resources in this assignment. Note: Wikipedia and other similar Websites do not qualify as academic resources
2. Write clearly and concisely about managing organizational change using proper writing mechanics.

The specific course learning outcomes associated with this assignment are:

• Evaluate the reactions to change including identifying signs of resistance and approaches to managing it.
• Evaluate strategies for communicating change.
• Use technology and information resources to research issues in managing organizational change.
• Write clearly and concisely about managing organizational change using proper writing mechanics.
• Evaluate strategies for communicating change.

Click here to view the grading rubric for this assignment.

Details:

The practice of health care providers at all levels brings you into contact with people from a variety of faiths. This calls for knowledge and acceptance of a diversity of faith expressions.

The purpose of this paper is to complete a comparative analysis of two faith philosophies towards providing health care, one being the Christian perspective. For the second faith, choose a faith that is unfamiliar to you. Examples of faiths to choose from: Sikh, Baha’i, Buddhism, Shintoism, etc.

In a minimum of 1,500-2,000 words, provide a comparative analysis of the different belief systems, reinforcing major themes with insights gained from your research.

In your comparative analysis, address all of the worldview questions in detail for Christianity and your selected faith.  Refer to chapter 2 of the Called to Care for the list of questions.  Be sure to address the implications of these beliefs for health care.

In addition answer the following questions that address the practical and healthcare implications based on the research:

What are critical common components to all religions/beliefs in regards to  healing, such as prayer, meditation, belief, etc.? Explain.

What is important to patients of the faiths when cared for by health care providers whose spiritual beliefs differ from their own?

In your conclusion, describe your own spiritual perspective on healing, what you have learned from the research and how this learning can be applied to a health care provider.

Support your position by referencing at least three academic resources (preferably from the GCU Library) in addition to the course readings, the Bible, and the textbooks for each religion. Each religion must have a primary source included. A total of six references are required according to the specifications listed above.  Incorporate the research into your writing in an appropriate, scholarly manner.

Prepare this assignment according to the APA guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to Turnitin. Please refer to the directions in the Student Success Center.

Please Note: Assignment will not be submitted to the faculty member until the “Submit” button under “Final Submission” is clicked.