Author: chris

COMPARE and CONTRAST the similarities and differences between ramipril/metoprolol with respect to pharmacokinetics and pharmacodynamics.
Use the non-proprietary (non-commercial) names for the drug pair throughout the essay. Apply resources such as journal articles, medical and scientific text books, and scientific web based resources (e.g. NIH website, American Heart Association website) to support your essay content. DO NOT use commercial non-government websites.

It is recommended to self-check your essay assignment by using the marking rubric provided.

The essay assignment will comprise;

1. A brief descriptive single short sentence title of approximately 10 words (see marking rubric for criteria);
2. Introduce both drugs and specify their actions and indications in a single paragraph;
3. The pharmacokinetics of each drug by comparing and contrasting the following;
a. Brief administration route of the drugs and then detail how the drugs are absorbed
b. Bioavailability and half-life of the drugs
c. Distribution of the drugs in the body
d. Metabolism of the drugs
e. Excretion of the drugs
4. Detail and compare the pharmocodynamics of the drugs. Include the following information:
a. Compare/Contrast the mechanism of action of the drugs. If this is currently unknown, what is it thought to be?
b. Identify the adverse drug reactions linked to the mechanism of action and explain why they occur.
Writing format. See notes under Presentation.

This assignment is designed to develop your ability to identify and communicate scientific details in a concise written format, using appropriate citation and reference page. The word limit is a maximum and markers are not required to read beyond the set word limit. This is in essay format and subheadings, dot points, figures and tables are NOT to be used. Remember that you are required to compare and contrast the characteristics of the drugs not just list the characteristics of each. The assignment should be written in a fluent and economical sentence structure in paragraph format and include correctly formatted citation and reference page according to APA referencing style. A copy of the APA Referencing guide is available in the Interact site and the citation and reference list formatting must rigidly adhere to this style (Marks will be deducted for incorrect formatting). The reference list page (in APA format) should follow the main section and would not be expected to contain more than 6 references including at least one recent journal article relevant to the topic.

The assignment file must be submitted via EASTS in *.doc, *.docx, or *.rtf format (not PDF), and include a word count below the references list.

Rationale
The purpose of this assessment item is to allow students to explore in greater detail important subject content areas.

This assessment item assesses the following learning outcomes provided in this subject outline (p.3):
* define common pharmacological terms;
* describe the four pharmacokinetic processes (absorption, distribution, metabolism and elimination);

Marking criteria
Marking criteria (total /20)

Professional Knowledge: 16 marks given for the descriptive title, the introduction, comparison of the drug pairs with respect to their pharmacokinetics and pharmacodynamics & side effects.

Academic Writing Conventions: This assignment is in the format of an essay style. 4 marks given for correct grammar/spelling, use of appropriate citation and references in APA format, use of appropriate scientific language and writing style. Please note that this is a bioscience assignment and extensive discussion of clinical care is not appropriate.

Name:
Assignment 1
Student Name:
Student Number:
Weighting:
Standards
Criteria
HD
DI
CR
PS
FL
1. Descriptive title informing the reader of the drug used to treat it including the drug class and basic mechanism.
(1 marks)
Title is concise and detailed. A simple short sentence that includes the drugs, drug classes. Clearly informs the reader of the content of the assignment.
Title is detailed. A simple short sentence that includes the drug, drug class and basic mechanism. Informs the reader of the content of the assignment but is not concise.
Title includes the drugs, drug class and basic mechanisms but is not concise or is lacking in detail.

Title present but lacks detail. Sentence is not concise or lacks detail.
Does not include one or more of the drug, drug class or the basic mechanism.
No title, short or overly long title or lacking detail of the drugs, drug class or mechanisms.
Unclear what the content of the assignment will be.
Potential marks
1
0.85
0.75
0.5
<0.5
2. Introduce the drugs.
Detailed single paragraph that presents a concise/essential comparison of the drugs so that the reader is clear on the essay content.
(3 marks)
Information flows in a proficient and logical format.
Succinct and detailed comparison of the chosen drugs that shows depth of knowledge in how the drugs are used to treat disease. Substantial integration of the drug class(es) and basic drug mechanisms.
Information flows in a substantially logical format.
Detailed description and comparison of the chosen drugs that substantially shows how the drugs are used to treat disease. Some integration of the drug class(es) and basic drug mechanisms.
Information flows in a mostly logical format .
Description that shows basic proficiency of how the drugs are used to treat disease. Includes some excess information. Describes the drug class(es) and basic drug mechanisms.
Information present but does not flow logically in parts. Includes too many details for an introduction. Description shows some understanding of how the drugs are used to treat disease but comparisons are not directly made. Describes some details of the drug class(es) and basic drug mechanisms.
Little to no logical flow of information. Does not undertake a drug comparison format. Missing details of the drug class(es) and basic drug mechanisms.
Potential marks
3
2.5
2
1.5
<1.5
3. Compare and contrast the pharmacokinetics of the drugs and how factors affecting absorption, distribution, metabolism and elimination impact on bioavailability and half-life.
(5 marks)
Succinct introduction to the drugs. Detailed description of the pharmacokinetics including how factors affecting absorption, distribution, metabolism and elimination are linked to the choice of delivery method(s), the bioavailability and half-life.
Substantial integration of pharmacokinetic factors evident with strong links made between these factors.
Mostly succinct introduction to the drugs. Includes all elements of pharmacokinetics. Describes most factors affecting absorption, distribution, metabolism and elimination and their impact on bioavailability and half-life.
Moderate integration of pharmacokinetic factors with links made between factors.
Introduction to the drugs showing drug comparisons. Pharmacokinetic elements present but lacks some details. Describes several factors affecting absorption, distribution, metabolism and elimination and their impact on bioavailability and half-life by linking these elements.
Some integration of pharmacokinetic factors with the links made between factors.
Inconsistent or very basic level of comparison.
Elements of the pharmacokinetics are missing or vague. Identifies some factors affecting absorption, distribution, metabolism and elimination and their affect on bioavailability and half-life.
Very little or basic integration of pharmacokinetic factors evident with the links made between factors.
The drugs are not introduced or described. Drug comparison lacking. Lacks detail of the pharmacokinetics. Does not display sufficient knowledge of the elements of pharmacokinetics.
Excess clinical information.
Potential marks
5.5
5
4
3
<3
4. Comparison of the drug pharmacodynamics
(6 marks)
Detailed and concise comparison of how the drugs manifest effects on the body.
Clearly describes and links how the drug mechanism may manifest side effects or adverse events.
Detailed comparison of how the drugs manifest effects on the body.
Describes how the drug mechanism may manifest side effects or adverse events.
Mostly detailed comparison of how the drugs manifest effects on the body and how the drug mechanism may manifest side effects or adverse events
Adequate comparison of how the drugs manifest effects on the body.
Lists the side effects or adverse events but provides few details on the links of how the drugs may manifest these.
Does not effectively follow a Compare and Contrast format;
Or lacks important information with regards to how the drug manifests effects on the body;
Or side effects/adverse events not included.
Potential marks
6
5
4
3
<3
5. Academic writing conventions and referencing.
(3 marks)
No errors in spelling and grammar.
Very effective sentence flow and paragraph format. Concise scientific writing.
Very limited errors in spelling and grammar.
Writing is mostly concise with effective sentence flow and paragraph format.
Minor spelling and grammar errors.
Writing is understandable with reduced instances where there is a lack logical flow of information, not concise, or be unscientific. Some instances of ineffective sentence flow and paragraph format.
A range of spelling and grammar errors.
Writing is understandable but has a range of instances where there lacks logical flow of information, not concise or is unscientific; or parts showing ineffective sentence flow and paragraph format.
Multiple spelling and grammar errors.
Writing is informal, illogical, not concise or unscientific; or shows ineffective sentences and paragraph format. Excessive word count. Use of direct quotations.
Potential marks
3
2.5
2
1.5
<1.5
6. APA Referencing
(2 marks)
Thoroughly complies with APA citation and reference page formatting.
Minor errors in compliance with APA citation and reference page formatting.
Some errors in compliance with APA citation and reference page formatting.
A range of errors shown with APA citation and reference page formatting.
Many inappropriate reference sources used such as commercial websites or those set up for general public education (ie non-academic);
Or little/no within paragraph citation included and/or a reference page included.
Potential marks
2
1.75
1.5
1
<1
Bonus mark for peer reviewed journal article inclusion (1 mark)
Multiple (>3) journal articles (peer reviewed)
Three journal articles (peer reviewed)
Two journal article (peer reviewed)
One journal article (peer reviewed)
Standard textbooks and substantial reliance on pharmacology database resources only.
Potential marks
1
0.75
0.5
0.25
0
Max mark possible is 20.
Total mark achieved:

Late penalty: Adjusted mark:
Comments:
Presentation
All written assignments in this subject must show the following presentation standards:

1½ line spacing and left-justified only
Times New Roman 12-point font
Paragraph format of approximately 4-8 sentences
Pages must be numbered and your name &/or student number appear in the footer of each page
Pages should be set to A4
Minimum of 2 cm margins around the text
Proof-read your work before submission – your work should be free of grammatical, spelling and typographical errors
Reference list must be in APA format
Students have access to TURNITIN in order to self-check their work for similarity to other authors. It is highly recommended to all students make use of this facility.

Requirements
Include a word count below the reference list. The word count is from start of first paragraph to end of final paragraph.

Assessment 1.5
Attached Files:
File Assessment 1.5 Points of Debate(1).docx (16.811 KB)

Assessment 1.5 – Points of Debate

Due: Week 8 – Monday 14 September by 10am

Submission: In class or via the submission link the Assessment 1.5 folder

Format: Times New Roman 12 point font (depending on the quantity or depth you wish to convey, you may use a dot-point style format on your summary of key points if required).

Weighting: 10%

Comprehension and critical thinking task

Task Instructions:

1. Select one of the three topics for debate from the following list

a) Decriminalisation or Legalisation of Marijuana

b) The Death Penalty

c) Voluntary Euthanasia

2. Research your topic using a mix of scholarly sources and reputable web sites.

3. List at least three key points in support of the issue. Provide additional information on each point using sub headings.

4. List at least three key points opposing the issue. Provide additional information on each point using sub headings.

IMPORTANT: Do not merely paraphrase or copy and paste the points made from websites. The idea is for YOU to consider each point and list what YOU think are the main arguments. You must demonstrate your understanding by expanding on the points or providing examples.

5. Complete the Assessment 1.5 Questionnaire (located in the Assessment 1.5 folder on the Learning@Griffith course site).

6. Attach Assessment 1.5 Questionnaire to your summary of key points (copy and paste onto a single Word Document) and submit.

Criteria:

a) Coverage of both sides of the debate

b) Breadth of arguments (i.e. multiple points)

c) Depth and/or innovation in discussion of relevant points

d) Evidence of critical thinking in summary of key points and questionnaire answers

e) Evidence of personal reflection in questionnaire answers

f) Writing (spelling, grammar, expression) & Referencing (APA)

Minimum References: 2 (but more is better) reputable internet sources are allowed for this task but scholarly sources are even better.

Assessment 1.5 Questionnaire
Attached Files:
File Assessment 1.5 Questionnaire.docx (16.474 KB)

Web links
Attached Files:
File A1.5 weblinks(1).docx (14.204 KB)
Here are some web links to sites with an overview of each of the debates to get you started. Please note this list is compiled from a brief Google search only, it is not exhaustive, nor do these sites necessarily constitute scholarly sources. It is up to you to determine the relevancy, reliability and/or truth of the points made herein. You do not need to use these sites specifically and many other resources will provide an overview of these debates. Happy researching!

Martha E Rogers: Science of Unitary Human Beings

Discussion of the theorist’s view of the four basic metaparadigms and two concepts unique to the theory.
Explain the discussion in four pags.
Please 5 references.

The four basic metaparadigms are:
Unitary Human Being (person)
Environment
Health
Nursing

The two concepts unique to the theory:
Energy field
Openness
Pattern
Pan dimensionality
Homeodynamic principles
Resonance
Helicy
Integrality
Please named the 8 concepts and select two unique concept for The discussion

• Discuss the main trends: for example, globalisation or the need for prior work experience in order to secure employment.
• Discuss the skills required for your chosen career /industry, identifying specific career/industry-related skills.
• Discuss more general and transferable skills such as written and verbal communication skills and the ability to work in a team.
Identify any skills gaps you may have and produce an action plan to meet those skills gaps.

Re: Project paper formatting guidelines
I trust you are working on your project paper. Please know that while writing your paper, it is necessary and required that you follow the steps below:

1. Abstract. Here you summarize your total paper briefly in a single paragraph. Objective, method, major findings – NO equation or detailed discussion.

2. Introduction. In this section you discuss what you are doing and why your work is important. In the end, a paragraph with your main findings is a must. This section is typically no longer than two pages.

3. Literature review. Discuss methods, data and results of several published research papers in the area of your work. Also explain how your work is important and different from those work. Around two pages is okay.

4. Data and Methodology. Clearly indicate type of data you are using and the source(s) of data. Detail the methodologies you would use in the paper. If you use multiple methods, all needed to be clearly elaborated with necessary equation and explanation.

5. Results and discussions. This is important that you explain your findings in detail and indicate that they are reasonable and realistic. If you have performed any hypothesis testing explain them. You must show your results in tables or graphs labeling serial number and titles. Large table can be attached in an appendix (Please don’t attach any data set with your paper).

6. Conclusion. This section summarize your forecasting results and you acknowledge constraints you have faced during your research work, e.g., methods, data. Based on that you indicate future research directions. This section should not be more than two paged long.

7. Bibliography. List all papers you have referred in you paper.

, 11 (arial) or 12(new times roman) size, and equation editor for equations.

we already have proposal that u can work on it.
Good luck on you project work.

It would be a good idea to look into the US National Security Strategy 2002 and analyse the impact in which it had on the definition of sovereignty; a good section of the essay should evaluate this piece of documentation.

A good structural idea in writing the essay would be roughly to keep to this:
Introduction – 312 words and Thesis – 50 words in the same paragraph

Road Map – 225 words discussing on what will be discussed within the essay

4 Paragraphs – 312 words each supporting the argument of the thesis

Anti thesis – 350 words discussing issues that go against the thesis, acknowledge and address possible criticisms of thesis

Conclusion – 312 words

Also you should be signposting between paragraphs by starting each argument by referring to the previous section.

Address the question or title; follow a structured and signposted sequence; demonstrate familiarity with the relevant literature to the concept of sovereignty; present an analysis and evaluation of the ideas and theories discussed; reveal internal integration and coherence; use references and examples to support the claims and arguments made; provide detailed references and sources in the bibliography or reference section; be written in good and grammatically correct English. Differences within the range are usually attributable to differences in the quality of analysis and evaluation and internal integration and coherence.

Good academic books to consider are:

Brown, C. (2006) Sovereignty, Rights and Justice, Polity

Chesterman, S. (2002) Just War or Just Peace?, Oxford University Press

Jackson, R. (2007) Sovereignty: Evolution of an Idea, Polity

Bain, W. (2003) Between Anarchy and Society, Oxford University Press

Booth, K. & Dunne, T. (2002) Worlds in Collision: Terror and the Future of Global Order, Palgrave

Cunliffe, P. et al (2007) Politics without Sovereignty, UCL Press

Chandler, D. (2010) International Statebuilding, Routledge

Chesterman, S. (2005) You the People, Oxford University Press

Hehir, A. (2013) Humanitarian Intervention: An Introduction, Palgrave

Hehir A. and Robinson, N. (2009) State-building: Theory and Practice, Routledge

Jackson, R. (1990) Quasi-states, Oxford University Press

Krasner, S. (1999) Sovereignty: Organized Hypocrisy?, Princeton University Press

Simpson, G. (2004) Great Powers and Outlaw States, Oxford University Press

Scheipers, S. (2009) Negotiating Sovereignty and Human Rights, Manchester University Press

Zaum, D. (2007) The Sovereignty Paradox, Oxford University Press

Examine and critically reflect upon the feedback given on your first assignment and draft a response to the feedback that demonstrates improvement on your work.

For example:

• If a comment made by the marker in coursework 1 is that greater linkage between a number of sources would improve the answer, you can make use of coursework 2 to demonstrate how the sources could be linked more closely.
• If a comment made by the marker in coursework 1 invites the student to conclude a particular argument, you can make use of coursework 2 to conclude that particular answer.
• If the marker of coursework 1 suggests that additional sources could be used to support a certain point, you can use coursework 2 to identify these sources and point to their relevance in answering the question.
• If minor points relating to grammar, syntax and referencing are made by the marker in coursework 1, you could demonstrate the correcting of these errors in coursework 2.
• If an element of coursework 1 is pointed out as being particularly good, you could make use of coursework 2 to ensure they understand why it was particularly good and also highlight how this could have been applied to other areas of their work.

OSCOLA REFERENCING ONLY

Imagine that you are working on a project to purchase 5,000 electrical generators with an electrical capacity of three (3) kilowatts and will be used by the U.S. Army for battlefield communications systems.

Choose to respond to this scenario from a government or a contractor perspective. If you select government, then you will complete the assignment as if you are a government employee (or military personnel) receiving the proposal from the contractor. If you select contractor, then you will complete the assignment as if you are a contractor employee submitting a proposal to the government.

Write an eight to ten (8-10) page paper in which you:

Evaluate the requirements for announcing federal contract awards. Determine how these requirements apply to this scenario.
Establish the responsibilities of the Contracting Officers Representative (COR) for this contract.
Evaluate the existing training and certification requirements for CORs in general.
Create a set of specific requirements for the COR working on the contract for 5,000 electrical generators.
Assess the importance of safeguarding proprietary information. Propose two (2) ways that proprietary information can be safeguarded in this scenario.

Use at least five (5) quality academic resources in this assignment. Note: Wikipedia and other Websites do not qualify as academic resources.

Your assignment must follow these formatting requirements:

Be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides; citations and references must follow APA or school-specific format. Check with your professor for any additional instructions.
Include a cover page containing the title of the assignment, the student’s name, the professor’s name, the course title, and the date. The cover page and the reference page are not included in the required assignment page length.

Please include Resources: Compton, P. B. (2010). Federal acquisition: Key issues and guidance. Vienna, VA: Management Concepts, Inc. Feldman, S. W., & Keyes, W. N. (2011). Government contracts in a nutshell (5th ed.). St. Paul, MN: Thomson Reuters.

Examine and critically reflect upon the feedback given on your first assignment and draft a response to the feedback that demonstrates improvement on your work.

For example:

• If a comment made by the marker in coursework 1 is that greater linkage between a number of sources would improve the answer, you can make use of coursework 2 to demonstrate how the sources could be linked more closely.
• If a comment made by the marker in coursework 1 invites the student to conclude a particular argument, you can make use of coursework 2 to conclude that particular answer.
• If the marker of coursework 1 suggests that additional sources could be used to support a certain point, you can use coursework 2 to identify these sources and point to their relevance in answering the question.
• If minor points relating to grammar, syntax and referencing are made by the marker in coursework 1, you could demonstrate the correcting of these errors in coursework 2.
• If an element of coursework 1 is pointed out as being particularly good, you could make use of coursework 2 to ensure they understand why it was particularly good and also highlight how this could have been applied to other areas of their work.

OSCOLA REFERENCING ONLY

1. What is the name of the governmental agency that regulates television and radio? 2. List the predominant television and radio networks/stations in the capital of Korean. 3. List the newspapers from the capital city of Korea. Circulation? 4. List the major national magazines in Korea. Circulation?