Describe the process of regulation of bulk fluid flow across capillaries. How would heart failure disrupt this process resulting in oedema?

Describe the process of regulation of bulk fluid flow across capillaries. How would heart failure disrupt this process resulting in oedema?

Introduction
The cardiovascular system comprises of the heart and blood vessels which both work together in keeping the continuous circulation of blood through the body (Marieb & Hoehn, 2014). This ensures a continuous supply of oxygen and nutrients to tissue cells and also prevents waste build up, a critical homeostatic need (Marieb & Hoehn, 2014). As well as gas and nutrient exchange the capillaries facilitate bulk fluid flow across capillary walls, important in regulating the relative fluid volume in the blood stream and interstitial space (tissue) (Marieb & Hoehn, 2014). When this homeostatic balance is disrupted it can lead to excess fluid draining into tissue and causing oedema (Marieb & Hoehn, 2014). This overload of fluid into the tissue can be caused by heightened pressure in the veins and capillaries as a result of heart failure (Hughes, 2013).

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