Do you think it is unethical to use a placebo in a clinical trial in a disease for which there is standard therapy available? Explain.

The current version of the Declaration of Helsinki discourages the use of placebos in instances where there is standard medical therapy available. However, there really is a placebo effect for certain classes of drugs that should be examined to determine the true effect of an active drug. Do you think it is unethical to use a placebo in a clinical trial in a disease for which there is standard therapy available? Explain your position.

second section:
Read the article from this past Sunday’s NY Times Business Section (A Drug Trial’s Frayed Promise) (http://nytimes.newspaperdirect.com/epaper/viewer.aspx). List 3 things that should have been done differently to avoid the problems that occurred during this trial.

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