Drug Interaction, Its Effects, and Prevention
Drug interaction refers to an interaction between a drug and other substances that might prevent the drug from functioning effectively. According to Iacobellis, interaction might occur between drug-to-drug and drug-to-food thereby leading to unintended effects (2). The purpose of this paper is to establish the causes of plavix interaction, its effects, and measures that can be used to prevent drug interaction.
The liver is supposed to breakdown plavix into its active form. According to Hamermesh, Aspinall, and Gordon, the liver uses the patient’s CYP2C19 to breakdown plavix into its active form (2). In other words, patients with even a single variant copy of CYP2C19 gene produce less 23.4% of the active drug. Such patients end up with a dose that is too low to produce the required anti-clotting effect. Drug interaction also occurs when two drugs that have similar or opposite effects on the body are administered together (Wolverton 817). For instance, when Plavix is administered together with prilosec, Plavix will not have the desired effects (protection against cardiac disease).
Dangers Associated with Plavix Interaction
Drug interaction might lead to under treatment. According to Hamermesh, Aspinall, and Gordon, Plavix interactions often lead to complications such as heart attack or stroke (1-2). Such diseases are very expensive to treat and might sometimes lead to death. Plavix interaction also leads to a blood clot. The blood clotting mostly occurs among patients with variant (12.1% versus 8.0%) and those with stent (2.6% versus 0.8%) (Wolverton 817-819). The fact that plavix cannot prevent cardiac attack when it is taken with prilosec implies that, those patients taking plavix and prilosec are at risk of prolonged cardiac complications.
Prevention of Plavix Interaction Complications
Patients under plavix dose should take a number of measures to prevent interactions. First, those patients should not take Prilosec while still under plavix dose (Hamermesh, Aspinall, and Gordon 4). This will enable Plavix to have control of the body once administered. Secondly, medical practitioners should confirm that, Plavix is only administered to patients with CYP2C19 genes because their liver has the capacity to breakdown Plavix into its active form.
Works Cited
Hamermesh, Richard G. Aspinall, Mara G. Gordon, Rachel. Plavix: Drugs in the Age of Personalized Medicine. (2010): 1-14. Print.
Iacobellis, Gianluca. Drug-drug Interactions in the Metabolic Syndrome. New York: Nova Science Publishers, 2006. Print.
Wolverton, Stephen E. Comprehensive Dermatologic Drug Therapy. Edinburgh: Saunders/Elsevier, 2013. Print.
Last Completed Projects
| topic title | academic level | Writer | delivered |
|---|
Are you looking for a similar paper or any other quality academic essay? Then look no further. Our research paper writing service is what you require. Our team of experienced writers is on standby to deliver to you an original paper as per your specified instructions with zero plagiarism guaranteed. This is the perfect way you can prepare your own unique academic paper and score the grades you deserve.
Use the order calculator below and get started! Contact our live support team for any assistance or inquiry.
[order_calculator]